Ministry of Science and Higher Education

The research will help to determine the role of vasopressin (AVP) in the regulation of the peripheral chemoreceptor reflex and whether there are changes in the regulation of the respiratory system by vasopressin in conditions of arterial hypertension.

It will also help to determine the role of vasopressin in the increased activity of the arterial chemoreceptor reflex in arterial hypertension and expand the knowledge of mediators and receptors involved in chemotransduction in carotid bodies chemoreceptors.

The research will help to broaden the understanding of the influence of the metabolic syndrome on the dysfunction of the endothelium of the heart blood vessels and to explain the mechanism of VEGF's autocrine action, which leads to impaired blood vessel formation and increased microvascular permeability in the heart. The isolated endothelial cells of the blood vessels of the heart of mice with metabolic syndrome, on which the research will be conducted, will allow to precisely determine the role these cells play in the pathogenesis of heart failure observed in this disease.

The aim of the project is to comprehensively investigate the process of natural killer (NK) cell migration and to select the best expansion strategy for NK cells to improve their migration to neoplastic cells. NK cells comprise 5-15% of blood lymphocytes and are characterized by the unique ability to spontaneously recognize and kill neoplastic cells. Their abilities play a role in the immune surveillance of tumors, and they have been used in adoptive anti-cancer therapies. In recent years, two key processes have been discovered and characterized in detail that allow NK cells to achieve full functionality and anti-cancer potential - education and differentiation process. The assessment of the impact of both processes on the ability of NK cells to migrate in order to better understand their physiological function in the human immune system and to characterize their migration potential to cancerous tumors or infected tissues is planned.

When setting the priorities for scientific research in Poland, the areas which give the Polish economy a chance for a competitive advantage are taken into account in particular. In the assumptions of the state's science, technology and innovation policy, the priority directions include research needed for, inter alia, increasing the competitiveness of products and services as well as improving the quality of life, in particular by protecting health and the environment. According to the national research program (National Research Programme (KPB), Annex to the Resolution No. 164/2011 of the Council of Ministers of August 16, 2011), one of the strategic interdisciplinary directions of research and development work is "diseases of civilization, new drugs and regenerative medicine". In the coming years, one of the main health threats to the population of Poland will be diseases of affluence, including malignant tumors. To counteract this, pharmaceutical companies undertake innovative projects in the area of ​​oncology. The proposed doctoral study program supports this area of ​​study, providing a solid foundation for the graduate to independently initiate and run projects in this field. It is also worth mentioning that the doctoral study program at the Faculty of Pharmacy of the Medical University of Warsaw covers issues in the field of industrial biotechnology, such as: production of advanced materials or innovative technological processes. These areas, according to the conclusions of the project "Technological Foresight of the InSight 2030 Industry", have a chance to become the driving force of the Polish economy and contribute to increasing the competitiveness and innovation of the Polish industry.

15th Warsaw International Medical Congress is the fifteenth jubilee edition of the international conference for Young Scientists organized by the Student Scientific Society of the Medical University of Warsaw. This year, it will be held on May 9-12, 2019 at the Didactic Center of the Medical University of Warsaw at 2a Trojdena St. This conference aims to enable young scientists from around the world to present the results of their research, broaden their knowledge in the field of biomedical sciences, acquire new practical skills and provide broadly understood promotion of science. It is addressed to students of biomedical faculties, doctoral students as well as young doctors and scientists from around the world. For years, we have been honored with the presence of world-class scientists from extremely diverse scientific fields who delivered the lecturers. Each of them is the best specialist in their field. For instance, during the 12th WIMC, we were honored by the presence of the Nobel Prize Winner in the field of Medicine - prof. Bert Sakmann. The 14th edition of the Congress was also unique, because we hosted prof. Robert Lefkowitz - Nobel Laureate in the field of chemistry. Due to the growing interest of the participants in the lectures, this year we invited equally interesting figures from the world of science. Our invitation was accepted by such personalities as: prof. Olivier Kurzai (Germany), prof. Marta Kwiatkowska (Great Britain), Dr. Emilie Karafillakis (Great Britain), Dr. Nadine Haram (Great Britain), Prof. Bohdan Pomahac (USA), Dr. David Casarett (USA).

"Extending online access to the metadata of scientific information resources of the Main Library of the Medical University of Warsaw by retrospective preparation of catalog descriptions of medical journals published in the years 1881-2012 - a task financed under Contract 778 / P-DUN / 2019 from the funds of the Minister of Science and Higher Education allocated for activities promoting science"

The aim of the work planned for implementation in the proposed task is to extend the online catalog information about the resources of the magazines of BG MUW. It is planned to make bibliographic records for 2,400 volumes of journals, published in the congress languages ​​- German and English, in the years 1881-2012, which constitute a valuable collection of information in the field of medicine and related sciences. Catalog work will be carried out in the Aleph integrated library system. Compiled records, with information on library resources, will be made available through the online catalog at the publicly available address: http://aleph.wum.edu.pl. The implementation of the task is part of the systematic process of increasing the range of online catalog information through the retrospective development of the library resources of the MUW Main Library and is a continuation of the work carried out under the applications financed from the Science Promoting Activity (DUN) funds in 2017-2018.

The MUW Main Library, as one of 11 libraries of medical universities in the country, plays an important role in the nationwide medical library and information network. It is the largest library in its group in terms of the number of collections and the second largest library with a medical profile in the Mazowieckie region. This makes it one of the most important institutions for people associated with the health service, interested in access to professional medical literature. In 2017, over 188,000 user visits were recorded, nearly 328,000 visits to the website, over 38,000 library information was provided, including over 19,000 catalog information. Pursuant to the provisions of the Act on Libraries of June 27, 1997 (as amended) in Chapter 6 Article 21 point 2, the Main Library of the Medical University of Warsaw, as a unit organized by the university, belongs to the group of scientific libraries. By supporting the research and teaching activities of the Medical University of Warsaw, it provides access to resources that are necessary to conduct scientific and research work and carry out tasks as part of academic education.

An important element of the process of making scientific and didactic materials available is providing information about the resources held. The basic tool used for this purpose is the online catalog. Maintained in the integrated Aleph system, the electronic catalog is available in two web locations from the MUW Main Library's website, as well as from the NUKAT level, with which MUW Main Library has been cooperating since 2011. The MUW Main Library's website gives the possibility of using catalog information in two ways: directly from the online catalog, located at the public address: http://aleph.wum.edu.pl and through the PRIMO multi-search engine, available at the public address:: http://primo.wum.edu.pl. The applied solution aims to obtain the greatest possible number of recipients of online catalog information. It takes into account various preferences of searching for information, and thus, providing users with access to various information and search tools: in the form of an online catalog, as well as multi-search engines whose functionality is similar to the functions of the most popular Internet search engines, e.g. Google. Thanks to the cooperation of MUW Main Library with NUKAT, catalog information is also available from the level of the largest central catalog in Poland. Indexing the information from NUKAT in the WorldCat OCLC database makes the MUW Main Library online catalog a global search tool. As part of the planned work, registration of the cataloged resource in the Central Catalog of Foreign Journals of the Central Medical Library is also planned. This catalog is a unique source of information on the availability of foreign scientific periodicals in the field of medical sciences in Polish medical libraries. The database is supplied with data from 53 medical libraries and is available to the public at: http://opac.gbl.waw.pl/cgi-bin/wspd_cgi_ckcz.sh/wc_opac.p

The presence of the MUW Main Library's catalog in the above-mentioned Internet locations, will allow the extensive use of descriptive metadata, prepared as part of the requested task, both nationally and globally. This will ensure greater access to information about the collections of MUW Main Library, which should translate directly into better use of the developed book collection, greater popularization of scientific achievements and the intensification of the creation of new publications. Extending the online catalog information about the resources of MUW Main Library journals will also contribute to an increase in the number of orders carried out under interlibrary loans, as well as an increase in the number of inquiries submitted via online forms available from the Library's website and by traditional means.

The works will be performed at MUW Main Library, by a qualified team with many years of experience in the field of developing library collections. Catalog descriptions will be created using Polish standards and recommendations for bibliographic description, based on internationally standardized ISBD (CR) cataloging rules, as well as the MARC 21 data input format.

Organization of the congress for young scientists: "15th Warsaw International Medical Congress for Young Scientists" - a task financed under Agreement 579/P-DUN / 2019 from the funds of the Minister of Science and Higher Education allocated to activities promoting science

15th Warsaw International Medical Congress is the fifteenth jubilee edition of the international conference for Young Scientists organized by the Student Scientific Society of the Medical University of Warsaw. This year it will be held on May 9-12, 2019 at the Didactic Center of the Medical University of Warsaw at 2a Trojdena St.

This conference aims to enable young scientists from around the world to present the results of their research, broaden their knowledge in the field of biomedical sciences, acquire new practical skills and provide broadly understood promotion of science. It is addressed to students of biomedical faculties, doctoral students as well as young doctors and scientists from around the world.

For years, we have been honored by the presence of world-class scientists from extremely diverse scientific fields with our presence who delivered their lecturers. Each of them is the best specialist in their field. For instance, during the 12th WIMC, we were honored by the presence of the Nobel Prize Winner in the field of Medicine - prof. Bert Sakmann. The 14th edition of the Congress was also unique, because we hosted prof. Robert Lefkowitz - Nobel Laureate in the field of chemistry.

Due to the growing interest of the participants in the lectures, this year we invited equally interesting figures from the world of science. Our invitation was accepted by such personalities as: prof. Olivier Kurzai (Germany), prof. Marta Kwiatkowska (Great Britain), Dr. Emilie Karafillakis (Great Britain), Dr. Nadine Haram (Great Britain), Prof. Bohdan Pomahac (USA), Dr. David Casarett (USA).

Last year, participants submitted a unique number of abstracts to the competition - 710 works from as many as 35 countries, including as far away as China, Ethiopia or even Canada. These works were presented at 24 scientific sessions. The Warsaw International Medical Congress is therefore a unique opportunity to present your scientific achievements to an experienced jury consisting of the most outstanding doctors in Poland. This year, a special guest was waiting for the participants of the Cardiology & Cardiosurgery session: prof. Jeffrey Michel from Texas A&M College of Medicine, who also sat on the Jury sharing his experience with young medical adepts. It is also an ideal opportunity to gain experience in public speaking. In the previous year, reviews were made by as many as 259 reviewers with a PhD or higher. During the congress itself, the works were assessed in terms of content by nearly 190 members of the jury with the academic degree of habilitated doctor or higher. During this year's edition of the 15th WIMC, we are planning 29 scientific sessions. Each of the selected works will undergo a review process by at least 3 reviewers from various research centers. We expect that the group of reviewers will include over 320 scientists this year.

In addition, we intend to continue the tradition introduced three years ago - the winners of selected scientific sessions will enter the competition during the Plenary Session. The winner of the 14th WIMC conference received a cash prize of PLN 5,000, which allowed him to travel to any foreign conference. People who won the 2nd and 3rd place were given the opportunity to do an internship at the Karolinska Institutet in Sweden, under the supervision of prof. Kenny Rodriguez-Wallberg and at the Universitätsklinikum Münster in Germany under the supervision of prof. Malec. Taught with many years of experience, this year we plan to donate financial prizes not only to the Congress Winners, but also to the winners of the 2nd and 3rd place.

Currently, WIMC is an event known among students and young doctors all over Europe, and is also gaining popularity on other continents. In the last two years, we have established numerous partnership agreements with Congresses around the world. This is conducive to, among other things, the exchange of experiences, insights and ideas, but also often establishing interesting contacts. WIMC is a rapidly developing conference, gaining more and more publicity every year. It gives its participants many extremely valuable opportunities: broaden their scientific horizons, compete in the scientific field, acquire the latest medical knowledge.

As part of the event, very important topics in the field of public health are discussed, and the cooperation established with the World Health Summit, held regularly in Berlin, allows participants to learn about issues related to public health problems around the world.

Warsaw International Medical Congress for Young Scientists has numerous partner conferences - over 30 congresses from around the world. Thanks to this, we create an impressive network of scientific cooperation.

The 15th Warsaw International Medical Congress for Young Scientists consists of the following elements:

- scientific sessions in which participants present the results of their own research,

- expert lectures by outstanding lecturers from Poland and abroad,

- workshops during which participants acquire and improve practical and clinical skills,

- entertainment program - banquet, integration meeting, tours around Warsaw,

- startup competition - 10 young inventors will present the results of their work, the author of the best-rated idea will win a cash prize for the development of the idea.

The project is of great clinical importance because it addresses important issues that may affect the survival of the transplanted kidney and the recipient. In addition, it is based on the latest methods of immunological monitoring of the recipient of the transplanted organ. Determining the presence and class of antibodies against the donor's tissue capacity antigens and determining their importance in predicting the emergence of humoral rejection may be of great importance for further patient management. If the research hypotheses are confirmed, DSA monitoring will play an important role in the future planning of care for a transplant patient.

The project opens up the possibility of creating criteria for modifying immunosuppressive therapy, organizing more frequent check-ups, and taking other steps to prevent transplant failure in the course of humoral rejection. In the long term, the results could help to reduce the number of people who develop kidney failure in a transplant.