A multicenter, randomized, double-blind, placebo-controlled study to evaluate the efficacy of immunosuppression in biopsy-proven virus negative myocarditis or inflammatory cardiomyopathy (IMPROVE-MC)
Acronym
IMPROVE-MC
Project Title
A multicenter, randomized, double-blind, placebo-controlled study to evaluate the efficacy of immunosuppression in biopsy-proven virus negative myocarditis or inflammatory cardiomyopathy (IMPROVE-MC)
Financing Institution
Medical Research Agency
Medical Research Agency
Lead
Kierownik Projektu - dr n. med. Krzysztof Ozierański, Główny Badacz - prof. dr hab. Marcin Grabowski
Subject
A multicenter, randomized, double-blind, placebo-controlled study to evaluate the efficacy of immunosuppression in biopsy-proven virus negative myocarditis or inflammatory cardiomyopathy (IMPROVE-MC)
Project Objective
The aim of the presented IMPROVE-MC study is to evaluate the efficacy and safety of 12-month immunosuppressive treatment with prednisone and azathioprine as compared to placebo combined with the standard therapy, in patients with viral negative MSM/inflammatory cardiomyopathy. An additional goal of the project is to develop a diagnostic and therapeutic pattern allowing for modification of MSM treatment guidelines ready for implementation in Polish and international healthcare systems.