Identification and investigation of epigenetic factors involved in the regulation of the self-renewal capacity of hematopoietic stem cells
Project Title
Identyfikacja i badanie czynników epigenetycznych zaangażowanych w regulację zdolności do samoodnowy komórek macierzystych krwiotworzenia
Financing Institution
Lead
dr Eliza Głodkowska-Mrówka
Project Objective
Finding the factors that control the blood formation process at such an early stage is of enormous importance, not only scientific, but also practical. Abnormal differentiation of hematopoietic cells underlies many diseases, such as leukemia, immune disorders, and some anemia. The possibility of "undoing" cell differentiation offers a technological opportunity to create new therapies and may find application in obtaining material for bone marrow transplants and other treatments.