Research into the risk of hernia formation in scars after transverse cuts in the epigastrium in patients operated for malignant neoplasms

Financing Institution
Lead
dr hab. Michał Grąt
Project Objective

The obtained results will allow to broaden the current state of knowledge regarding factors related to the formation of hernias after abdominal surgeries performed with transverse cuts, which differ significantly from midline cuts in terms of the anatomy of the cut structures, blood supply to the wound edges and the forces acting on it. Currently available data do not allow any reliable evaluation of the importance of the technique of abdominal wall closure with transverse incisions within the epigastric region. Apart from very preliminary results, the results obtained so far do not allow to determine the importance of glycation end-products in the pathogenesis of postoperative hernias, and the results of studies on the influence of changes in the collagen content remain inconclusive. In addition to improving the current knowledge, the results obtained may in the future lead to the development of a strategy for more effective assessment and reduction of the risk of hernia formation.